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HomeTesting / ServicesAntibiotic Resistance Surveillance Program
Antibiotic Resistance Surveillance Program   Printable version

Invasive Disease Reporting

The Iowa Antibiotic Resistance Surveillance Program is a statewide, population-based study gathering information on the prevalence of invasive organisms - isolated from selected, sterile body sites - that show increased resistance to multiple drugs

These organisms are:

  1. Methicillin resistant Staph aureus (MRSA)
  2. Streptococcus pneumoniae
  3. Enterococcus species, including Vancomycin Resistant Enterococcus (VRE)
  4. Streptococcus pyogenes (Group A beta strep)
  5. Staphylococcus aureus with increased susceptibility to Vancomycin (VISA/VRSA)- These organisms are to be submitted regardless of site of infection

Eligible facilities (those labs performing susceptibility testing on these organisms) submit these organisms to the University Hygienic Laboratory along with their susceptibility results. Antimicrobial susceptibility testing is then repeated using the gold standard of broth microdilution to facilitate accurate evaluation of results. Only those drugs tested by our reference laboratory are included in the data displayed on this site.

Statewide Data
1999 2000 2001 2002 2003 2004 2005 2006 2007
Total Streptococcus tococcus 532 387 261 307 307 256 251 289 381
# Penicillin non-susceptible (%) 129 (24%) 110 (28%) 71 (27%) 67 (22%) 76 (25%) 38 (15%) 63 (25%) 80 (28%) 86 (22.5%)
# MDR (%)1 84 (16%) 71 (81%) 41 (16%) 32 (10%) 50 (16%) 23 (9%) 43 (17%) 52 (18%) 45 (12%)
# Levofloxacin non-susceptible (%) 1 (0.2%) 5 (1.3%) 0 3 (1%) 3 (1%) 2 (1%) 2 (1%) 3 (1%) 0
Total Enterococcus species 186 161 159 153 183 213 280 343 361
# VRE (%)2 27 (15%) 22 (14%) 29 (18%) 20 (13%) 30 (16%) 35 (16%) 40 (14%) 35 (10%) 33 (9%)
Total Streptococcus pyogenes 63 61 39 33 60 45 34 40 65
# Macrolide Resistant (%)3 0 2 (3%) 4 (7%) 4 (10%) 0 0 0 4 (10%) 3 (5%)
Total MRSA4 102 125 198 165 195 237 272 345 445

Disclaimer: The number of invasive infections caused by these organisms is most likely higher than represented here. A recent evaluation of this system revealed that only about 44% of the isolates that should be submitted to the surveillance program were actually submitted.

  1. MDR=Multi-Drug Resistant: Isolates of Streptococcus pneumoniae resistant to Penicillin and one or more of the following drugs: Erythromycin, Azithromycin, Clarithromycin, Clindamycin, Chloramphenicol, Tetracycline, Trimethoprim/Sulfa
  2. Vancomycin Resistant Enterococcus
  3. Macrolide non-susceptible represents isolates with reduced susceptibility to Clarithromycin. Azithromycin is no longer tested against Group A Strep in this program.
  4. Methicillin Resistant Staphylococcus aureus
    Note: no Staph aureus with reduced sensitivity to Vancomycin were identified through 2006 in Iowa
    2007: 2 VISA isolates, one from urine and one from blood; one from region 1A and one from region 2A

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